Surely people should have seen this coming. The body is designed to operate and develop in a certain natural manner. Corrective actions should only be taken when the body is functioning outside of the intended normality. To alter normality is going to result in impacts in ways that the body is going to reject, even if it is merely the mind. But when God is taken out of the equation, normality becomes defined by erring human beings, and people are the ginny pigs. "Be not wise in thine own eyes: fear the LORD, and depart from evil. It shall be health to thy navel, and marrow to thy bones" (Proverbs 3:7-8).